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Some Journals opt to use EM’s ‘Reference Checking’ tool, which will automatically check the validity of the references listed in each manuscript’s bibliography.
Reference Checking will attempt to find each Journal citation in PubMed and/or CrossRef. However, Reference Checking will not search for books or in press articles, as these texts are not listed in PubMed or CrossRef. If the Reference Checking tool is able to find the citation in PubMed and/or CrossRef, a link to that citation is created.
If the Journal has Reference Checking enabled, you will see a link that says “View Reference Checking Results”:

Clicking on the ‘View Reference Checking Results’ link will allow you to see the results of the reference check:

If the bibliographic entry is listed and ‘Validated’, then the reference checker was able to find a match in either PubMed or Cross Ref, or both. If the entry is listed as ‘Not Validated’, Reference Checker was not able to locate the citation in CrossRef or Pubmed.
Journal citations that cannot be matched with an entry in either PubMed or Cross Ref will be listed as either ‘Not Validated’ (see #6 in the figure above), meaning the tool views the citation as a Journal reference but cannot locate it on PubMed or CrossRef OR as Not Checked (see #3 above), meaning the citation does not appear to be from a Journal.
You should view your Reference Checking Results and attempt to resolve any problems with your references prior to submitting.